Sunday, April 22, 2007
What is Mesothelioma?
Mesothelioma is one of the deadliest diseases known to man; the average life span of an inflicted person from the time of diagnosis until death is less than 24 months. It’s a disease that strikes approximately 3,000 United States citizens each and every year; hard working people who have labored for a lifetime to provide for their families, doing the work that keeps this country running and a great place to live. They worked in factories, at shipyards, in mines, for the US military, as engineers, as pipefitters, as steel workers, as auto mechanics, and in so many other professions. They came home to their loved ones exhausted and covered in dirt and dust; tired, but content that they had a job and were providing for their family. Content that they were putting food on the table and a house over their loved one’s heads. Content that they were working to make a better life for their families in this generation and the next...



But what they didn’t know was that while they were working so hard, they were not only slowly killing themselves, but those that they were working so hard to help; their family, their loved ones.

Mesothelioma is a disease that is almost 100% preventable; the only known cause is via exposure to the deadly mineral Asbestos. It comes from inhaling the particles of dust as the asbestos degrades; eating away at the lining of your lungs and developing into a deadly cancer. Dust that was inhaled in clouds of white powder, dust that was carried home on the clothes of the men who built this country, dust that was cleaned from the clothes by the wives and children who supported their sole provider at home, dust that was packed around the heating systems in houses and offices and schools, dust that carried a deadly price; and dust made a fortune in blood money for the companies that produced it.

Unfortunately, the effects of asbestos on the human body were known to be deadly for years by the companies who employed the ‘greatest generation’ and made hundreds of millions, if not billions, of dollars off of their backs. But instead of taking simple steps to alleviate the problem and save the lives of thousands of their workers, they choose to do nothing and continue to make a “healthy” profit with a “deadly” product. Many even went so far as to hide the truth from their workers and their families. And because the normal latency period for Mesothelioma (The time from exposure until the patient falls ill) is 20 to 30 years, many got away with this for years. We are only now beginning to see the full effects of the disease, and feel the terrible outcry of the people against those who put profits before human lives to a degree that is simply unfathomable.

MesoLink.org is a site created to provide you with up to date information on the deadly disease Mesothelioma. We strive to provide the most complete overview of the disease and all aspects of it. This includes general information on the disease, breaking news on the search for a cure and perspective legislation designed to limit you as well as all other news on the subject, links to other sites and online resources that can provide important and in-depth Mesothelioma and cancer related information, and a legal guide to help you with the complex legal issues involved with Mesothelioma.


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posted by proletar @ 3:20 AM   0 comments
What is Mesothelioma (Asbestos Cancer)?
It is a form of cancer in which malignant (cancerous) cells are found in the mesothelium which is a protective sac that covers most of the body's internal organs. Generally, most individuals who develop this cancer have worked on jobs or lived in apartments or buildings where asbestos particles were inhaled.

Asbestos cancer is when the mesothelium lining becomes abnormal and grows uncontrollably causing pain. This can be benign or malignant. The malignant form of the cancer will damage the tissue of the organ it resides on and possibly invade other organs. Most cases of mesothelioma are either pleural or peritoneal. the Most cases of begin in the pleura or peritoneum.




Mesothelium has different names, depending on its location in the body. The peritoneum is the mesothelial tissue that covers most of the organs in the abdominal cavity. The pleura is the membrane that surrounds the lungs and lines the wall of the chest cavity. The pericardium covers and protects the heart. The mesothelial tissue surrounding the male internal reproductive organs is called the tunica vaginalis testis. The tunica serosa uteri covers the internal reproductive organs in women.

This site is dedicated to providing advice that can help those with questions concerning asbestos cancer.


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posted by proletar @ 3:19 AM   0 comments
Mesothelioma-Asbestos In My Body?
Mesothelioma is a cancer which is linked to exposure to asbestos fibers in 70 to 80 percent of cases. The National Cancer institute defines malignant mesothelioma as "a rare form of cancer...a disease in which cancer (malignant) cells are found in the sac lining the chest (the pleura), the lining of the abdominal cavity (the peritoneum) or the lining around the heart (the pericardium)." It is one of the most deadly cancers known to man; the average life span of an afflicted person from the time of diagnosis until death is less than 24 months.




Mesothelioma developes in approximately 3,000 United States citizens every year. Most of those diagnosed have a history of occupational exposure to asbestos, though a few have environmental or household contact. This cancer has an extremely long latency period; an exposure period of as little as one or two months can result in a mesothelioma up to 50 years later. Patients who had contact with asbestos as far back as the 1940s are now being diagnosed with this disease. In fact, the average time between exposure and the development of mesothelioma is 35-40 years.

When asbestos first came into use, its risks were unknown, and it was widely used as a fire-retardant material. Many people worked with this deadly substance, unaware that it would kill them several decades later. Workers such as bricklayers, insulaters, plasterers, electricians, mechanics, carpenters, and other tradesmen were exposed to asbestos on a daily basis as it was contained in many insulation and construction materials.

Even occassional exposure to asbestos is a health risk, and there have been many cases of mesothelioma developing in patients who only had brief contact, such as wives of asbestos-exposed workers who washed their husbands' overalls.

Due to the long latency period and vague, diffuse initial symptoms, there is often a delay in accurate diagnosis. As with many cancers, early symptoms can be mild and non-specific. Often patients present with only shortness of breath and a persistent cough; some show no symptoms at all in the initial stages, and the disease is first noticed on a routine chest X-ray. One early tell-tale sign is pleural effusion, a collection of fluid in the lungs. The right lung is affected 60% of the time, bilateral involvement being seen in 5% of cases. Less common initial complaints due to lung mesothelioma are fever, night sweats, weight loss, a raspy voice and facial swelling. Peritoneal mesothelioma can cause abdominal symptoms such as pain, abdominal swelling, nausea, weight loss, bowel obstruction, anemia and swelling of the feet. As the disease progresses, patients often develop severe cachexia (wasting).

One of the most common symptoms of mesothelioma, pleural effusion, is an accumulation of fluid between the parietal pleura, which covers the chest wall and diaphragm, and the visceral pleura, which covers the lungs. Both membranes are covered with mesothelial cells which, under normal conditions, produce a small amount of fluid that acts as a lubricant between the chest wall and the lung. Any excess fluid is removed via blood and lymph vessels, thus maintaining a balance. When more fluid is produced than can be absorbed, an effusion forms.

These effusions are called either transudates and exudates. A transudate is a clear fluid that forms not because the pleural surfaces are diseased, but because of an imbalance between the normal production and removal of the fluid. Often this is caused by congestive heart failure. An exudate, which contains many cells and proteins and is often cloudy in color, results from disease of the pleura itself, and is common to mesothelioma. To differentiate between a transudate or an exudate, a diagnostic thoracentesis, in which a needle or catheter is used to obtain a fluid sample, may be conducted.

As the volume of excess fluid increases, symptoms develop such as shortness of breath (dyspnea) , chest pain, or a non-productive dry cough. Heard through a stethoscope, normal breath sounds are muted, and tapping on the chest will reveal dull rather than hollow sounds.

A pleural effusion can be seen with a chest X-ray, ultrasound or CT scan. Since pleural effusions are often caused by congestive heart failure, the discovery of an effusion is not in itself immediately suggestive of a malignant process.

A histological examination of pleural fluid is negative in 85% of cases; a definitive diagnoses is more often is obtained by a needle biopsy or surgical biopsy of pleural tissue.

Symptomatic treatment of lung compression caused by effusion is accomplished by application of a sclerosing agent which eliminates the space between the lung and the chest cavity, a process called chemical pleurodesis. Talc is usually used, with a success rate of 95%. It can be administered either as a powder or as a slurry mixed with saline. A surgical team opens the chest wall, removes the effusion, then collapses the lung before applying the talc. Once the lung is fused to the chest wall, an effusion can no longer accumulate and compress the lung. This is strictly a palliative measure to improve the patient's quality of life, and has no effect on the progression of the disease.

Attemps to cure mesothelioma utilize surgery to remove diseased tissue, combined with chemo and raiotherapy. Several new treatment modalities are currently being investigated. These include Photodynamic therapy, which uses light of particular frequencies to target and kill cancer cells which, compared to normal tissue, display increased uptake of photosensitizing drugs; immunotherapy, which fights the abnormal cells through stimulation of the body's own immune system; and Intensity Modulated Radiation Therapy, which is a radiation treatment that attempts to target just the malignancy, thus avoiding damage to adjacent healthy cells and tissue. In addition, some success has been acheived with the chemotherapeutic drug Alitma (pemetrexed). However, despite the number of clinical trials currently underway, as of the date of this article the prognosis for mesothelioma sufferers is still extremely poor.




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posted by proletar @ 3:17 AM   0 comments
Pericardial Mesothelioma Treatment by William Johnston
Pericardial Mesothelioma is an extremely difficult cancer to treat and presently, all treatment methods used have a poor success rate. The chances of a patient's survival depend largely on how early and how aggressively the cancer is treated. If pericardial mesothelioma is treated when it has fully matured and developed then the chances of survival are very slim and the prognosis for a patient could be only a couple of months. The latency period of pericardial mesothelioma (30 - 50 years), and its symptoms which are ordinary of other more common diseases such as pneumonia, make it extremely difficult to diagnose and therefore difficult to treat in its early stages. In this way, a lot of pericardial mesothelioma treatments do not aim to cure patients but instead focus on reducing the symptoms.




Before a patient is treated, a doctor will evaluate him or her, and afterwards decide which treatment method is most suitable for the patient's situation. The patient's age, medical history, general well being and even weight are taken into account before the doctor will decide which of the three treatments are most appropriate. These treatments are surgery, chemotherapy and radiation therapy.

Surgery

There are two different types of surgery that can be used one of which is called aggressive surgery. This is the most dangerous of all the treatment methods available and only the fittest of people are deemed strong enough to undergo this. Aggressive surgery consists of removing large chunks of cancerous cells from inside the patient. This is extremely dangerous in the case of pericardial mesothelioma seeing as the cancerous cells are in extremely close proximity to vital organs such as the heart and lungs. Extremely skilled surgeons are needed to perform this operation.

The second type of surgery is palliative procedures and this type of surgery is used only for the purpose of reducing the symptoms of the cancer. Palliative procedures are performed when pericardial mesothelioma is in its latest stages and is practically impossible to cure.

Chemotherapy

Chemotherapy is the most well known cure of cancers and involves using drugs to kill of cancerous cells. However, many of the drugs used do not have a high success rate although researchers are discovering new combinations of drugs that work more effectively. Many pharmaceutical companies are also endeavouring to find new drugs. Researchers predict that they will soon discover a drug with a significantly improved success rate.

Radiation Therapy

This form of treatment uses doses of radiation to kill cancerous cells. However, in the case of pericardial mesothelioma this is extremely difficult because as well as damaging cancerous cells, the radiation also damages vital organs such as the heart and lungs. This makes using radiation therapy most effectively extremely difficult. The dose of radiation is usually too weak to make a significant impact on curing pericardial mesothelioma.

Dual Therapy

Dual therapy is just a combination of surgery, chemotherapy and radiation therapy. This consists of using surgery to remove the majority of the cancer cells and then using chemotherapy and radiation therapy to kill off any remaining cells. This has proved to be an effective treatment method however also very dangerous. Only the fittest young people are able to undergo this treatment.
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posted by proletar @ 3:15 AM   0 comments
Mesothelioma (Asbestos Cancer) Symptoms
Symptoms may not show up in the body until between 20 - 50 years after exposure, which is why so many new cases of this form of cancer are being diagnosed in recent years. All though the dangers of asbestos cancer were realized many decades ago and precautions have been taken to reduce the risk of the disease, it can take very little exposure to cause the cancer.

As with many forms of cancer, the asbestos cancer tumor can spread in the body rapidly, often infecting the opposite pleura and continuing on to other internal organs. The symptoms of Asbestos cancer are listed below.






Pleural Mesothelioma:
* Shortness of breath
* Chest pain in the chest (caused by fluid accumulation in the pleura)

Peritoneal Mesothelioma
* Weight loss
* Abdominal pain
* Abdominal swelling (caused by fluid build-up in the abdomen)
* Bowel obstruction
* Blood clotting abnormalities
* Anemia
* Fever

If the asbestos cancer has spread beyond the mesothelium to other parts of the body, additional symptoms may include:
* Pain
* Trouble swallowing
* Swelling of the neck or face areas

If you are experiencing these or similar medical problem, please consult your doctor.


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posted by proletar @ 2:11 AM   0 comments
About Mesothelioma

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